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Sinoporphyrin sodium

NMR下載 COA and HPLC MSDS下載
names：
3,3'-(7-(1-(1-(13,17-bis(2-carboxylatoethyl)-3,8,12,18-tetramethyl-7-vinylporphyrin-2-yl)ethoxy)ethyl)-3,8,13,17-tetramethyl-12-vinylporphyrin-2,18-diyl)dipropionate tetrasodium
CAS號：
1820582-41-9
MDL Number：
MF(分子式)： C68H66N8Na4O98- MW(分子量)： 1231.2865
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	3,3'-(7-(1-(1-(13,17-bis(2-carboxylatoethyl)-3,8,12,18-tetramethyl-7-vinylporphyrin-2-yl)ethoxy)ethyl)-3,8,13,17-tetramethyl-12-vinylporphyrin-2,18-diyl)dipropionate tetrasodium
英文別名	Sinoporphyrin sodium; DVDMS; sinoporphyrin; DVDMS Free
CAS號	1820582-41-9
Inchi	InChI=1S/C68H70N8O9.4Na/c1-13-41-31(3)47-23-49-33(5)43(15-19-63(77)78)57(71-49)29-59-45(17-21-65(81)82)35(7)51(73-59)27-61-67(37(9)53(75-61)25-55(41)69-47)39(11)85-40(12)68-38(10)54-26-56-42(14-2)32(4)48(70-56)24-50-34(6)44(16-20-64(79)80)58(72-50)30-60-46(18-22-66(83)84)36(8)52(74-60)28-62(68)76-54;;;;/h13-14,23-30,39-40,69,72-73,76H,1-2,15-22H2,3-12H3,(H,77,78)(H,79,80)(H,81,82)(H,83,84);;;;/q;4*-1/p-4/b47-23-,48-24-,49-23-,50-24-,51-27-,52-28-,53-25-,54-26-,55-25-,56-26-,57-29-,58-30-,59-29-,60-30-,61-27-,62-28-;;;;
InchiKey	DVJUUYCXZVLGRJ-FLLOIMQSSA-J
分子式 Formula	C68H66N8Na4O98-
分子量 Molecular Weight	1231.2865
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Sinoporphyrin sodium(CAS:1820582-41-9 ):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Sinoporphyrin sodium, also known as DVDMS, is a photosensitizer that shows potential in both sonodynamic therapy and photodynamic therapy. Sinoporphyrin sodium significantly suppressed cell proliferation, promoted early apoptotic response, triggered collapse of F-actin filaments and inhibited cell migration. Sinoporphyrin sodium potentially a treatment for cancer.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Shi R, Li C, Jiang Z, Li W, Wang A, Wei J. Preclinical Study of Antineoplastic Sinoporphyrin Sodium-PDT via In Vitro and In Vivo Models. Molecules. 2017 Jan 11;22(1). pii: E112. doi: 10.3390/molecules22010112. PubMed PMID: 28085075.

[2]Shi R, Lin X, Zhang J, Jin H, Wang A, Wei J. Safety evaluation of repeated intravenous infusion of sinoporphyrin with and without PDT in rats. Photochem Photobiol Sci. 2016 Nov 2;15(11):1366-1376. PubMed PMID: 27714312.

[3] Wu L, Wang X, Liu Q, Wingnang Leung A, Wang P, Xu C. Sinoporphyrin sodium mediated photodynamic therapy inhibits the migration associated with collapse of F-actin filaments cytoskeleton in MDA-MB-231 cells. Photodiagnosis Photodyn Ther. 2016 Mar;1

3:58-65. doi: 10.1016/j.pdpdt.2015.12.008. PubMed PMID: 26742781.

[5] Yan X, Niu G, Lin J, Jin AJ, Hu H, Tang Y, Zhang Y, Wu A, Lu J, Zhang S, Huang P, Shen B, Chen X. Enhanced fluorescence imaging guided photodynamic therapy of sinoporphyrin sodium loaded graphene oxide. Biomaterials. 2015 Feb;4

2:94-102. doi: 10.1016/j.biomaterials.2014.11.040. PubMed PMID: 25542797; PubMed Central PMCID: PMC4280503.

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